When we think of aging, we often envision wrinkled skin, sagging bones, and brittle hair. These are all part of the aging process but what if we didn’t have to go through this as our bodies simply don’t age? That is what Gene Therapy does. It replaces our body’s genetic code with the genes of another person that causes our body to function correctly. This is done by inserting a DNA copy of a healthy donor into the patient’s body.
For a person who is interested in finding out what potential does gene therapy has for our lifespan, they first need to understand how it works. This treatment uses healthy tissue to treat cancerous cells. Basically, these are stem cells that have been modified to attack cancerous cells when they are not in an appropriate state. In addition to that, some of these stem cells will also be used to replace damaged or dead brain cells that have already been removed during the treatment process. These stem cells will not be harmful to your body in any way, and in fact they will help to rejuvenate your body and bring back the health that you had when you were younger.
In nature, gene regulation is primarily carried out by enzymes called transcription factors, which cause chromatin to change from its unorganized state into a more structured state. This regulation causes genes to be expressed, and the expression of those genes depends on the ability of the cells to convert DNA into RNA (ribonucleic acid).
Scientists have, for years now, been experimenting with how to treat the human condition at its most basic levels. That is, by altering the building blocks themselves, which make up our biology. While we are, at the moment, taking baby steps into this brave new world, it would seem inevitable that at some point in our future, near or far as that may be, science will tame our genetic code. Instead of going to the beauty parlor, will we simply be able to turn on a gene for blonde hair? Will we be able to live out extended lives in a disease free body, designed to our own exacting standards?
In 2013, a study by David Sinclair of Harvard and his colleagues reported that the mitochondria in lab mice was restored to youthful productive levels when treated with NMN (nicotinamide mononucleotide), a substance which boost levels of NAD in the body. Such a study speaks well to the success of increasing NAD in our own bodies, and the benefits to be gained from doing this. Increased levels of NAD can rejuvenate our mitochondria to the point where it acts like its more youthful self, allowing us, in turn, to rebound to our own youthful vigor while decreasing the threat of so many all too common degenerative ailments.